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-means clustering 1

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K<sup>+sup> and Na<sup>+sup> fluxes in roots of two Chinese Iris populations

Pinfang LI,Biao ZHANG

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 2,   Pages 144-149 doi: 10.15302/J-FASE-2014016

Abstract: Maintenance of ion homeostasis, particularly the regulation of K and Na uptake, is important for allObservations on ionic response to salinity and net fluxes of K , Na in the root exhibited by plantsNet fluxes of K , Na from the apex and along the root axis to 10.8 mm were measured using non-invasiveThere was a lower net efflux of K found in population Xj than by Bj in the mature zone (approximatelyPopulation Xj of continued to grow normally under NaCl stress, and maintained a higher K /Na ratio

Keywords： Koidz     population     K<sup>+sup> and Na<sup>+sup>     ion flux     non-invasive micro-test technique    

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Symbiotic performance, shoot biomass and water-use efficiency of three groundnut (

Sofiya K. MUHABA, Felix D. DAKORA

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 4,   Pages 455-466 doi: 10.15302/J-FASE-2020354

Abstract: phosphorus × genotype interaction was also significant for shoot DM, N content, N-fixed and soil N uptake

Keywords： shoot yield     N-fixed     %Ndfa     δ<sup>15sup>N     δ<sup>13sup>C     water-use efficiency    

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PtHAK5, a candidate for mediating high-affinity K

Haili YANG, Weidan ZHANG, Weiwei CHAI, Wenying WANG, Li GAO, Jing ZHANG, Yongping WANG, Suo-Min WANG

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 1,   Pages 108-117 doi: 10.15302/J-FASE-2018200

Abstract: The HAK5 K transporters generally modulate effective K acquisition in plants, especially under lowK condition.PtHAK5 consisted of 784 amino acids and shared over 80% homology with the identified high-affinity KThe expression of rescued the K -uptake-defective phenotype of yeast strain CY162.In conclusion, PtHAK5 is a candidate for mediating high-affinity K uptake under low K conditions.

Keywords： K<sup>+sup> uptake     PtHAK5     Puccinellia tenuiflora     yeast complementation    

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Study on Algorithm A<sup>*sup> Based on Dynamic Representation of Binary Tree for Environment and Robotic

Tang Ping,Yang Yimin

Strategic Study of CAE 2002, Volume 4, Issue 9,   Pages 50-53

Abstract: A new algorithm A<sup>*sup> , which plans the path of soccer robots in complicated environments is

Keywords： dynamic binary-tree     algorithm A<sup>*sup>     path planning    

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Clinical significance of CD34<sup>+sup>CD117<sup>dimsup>/CD34<sup>+sup>CD117<sup>brisup> myeloblast-associated

Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 608-620 doi: 10.1007/s11684-021-0836-7

Abstract: t(8;21)(q22;q22) acute myeloid leukemia (AML) is a highly heterogeneous hematological malignancy with a high relapse rate in China. Two leukemic myeloblast populations (CD34 CD117 and CD34 CD117 ) were previously identified in t(8;21) AML, and CD34 CD117 cell proportion was determined as an independent factor for this disease outcome. Here, we examined the impact of CD34 CD117 /CD34 CD117 myeloblast-associated gene expression on t(8;21) AML clinical prognosis. In this study, 85 patients with t(8;21) AML were enrolled. The mRNA expression levels of CD34 CD117 -associated genes ( , , and ) and CD34 CD117 -associated genes ( , , and ) were measured using quantitative reverse transcription PCR. Associations between gene expression and clinical outcomes were determined using Cox regression models. Results showed that patients with high , , or expression had significantly inferior overall survival (OS), whereas those with high or expression showed relatively favorable prognosis. Univariate analysis revealed that CD19, CD34 CD117 proportion, mutation, minimal residual disease (MRD), and expression levels of , , , and were associated with OS. Multivariate analysis indicated that mutation, MRD and and expression levels were independent prognostic variables for OS. Identifying the clinical relevance of CD34 CD117 /CD34 CD117 myeloblast-associated gene expression may provide new clinically prognostic markers for t(8;21) AML.

Keywords： t(8     21)(q22     q22) AML     CD34<sup>+sup>CD117<sup>dimsup>/ CD34<sup>+sup>CD117<sup>brisup> cell population    

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Removal of ammonium and nitrate through Anammox and FeS-driven autotrophic denitrification

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 6, doi: 10.1007/s11783-023-1674-4

Abstract:

● Simultaneous NH4<sup>+sup>/NO3<sup>–sup

Keywords： Anammox     Denitrification     FeS     NH4<sup>+sup>/NO3<sup>−sup>     Sulfammox    

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Selective recovery of Cu

Haiping LUO,Bangyu QIN,Guangli LIU,Renduo ZHANG,Yabo TANG,Yanping HOU

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 3,   Pages 522-527 doi: 10.1007/s11783-014-0633-5

Abstract: As the bioelectrochemical system, the microbial fuel cell (MFC) and the microbial electrolysis cell (MEC) were developed to selectively recover Cu and Ni ions from wastewater. The wastewater was treated in the cathode chambers of the system, in which Cu and Ni ions were removed by using the MFC and the MEC, respectively. At an initial Cu concentration of 500 mg·L , removal efficiencies of Cu increased from 97.0%±1.8% to 99.0%±0.3% with the initial Ni concentrations from 250 to 1000 mg·L , and maximum power densities increased from 3.1±0.5 to 5.4±0.6 W·m . The Ni removal mass in the MEC increased from 6.8±0.2 to 20.5±1.5 mg with the increase of Ni concentrations. At an initial Ni concentration of 500 mg·L , Cu removal efficiencies decreased from 99.1%±0.3% to 74.2%±3.8% with the initial Cu concentrations from 250 to 1000 mg·L , and maximum power densities increased from 3.0±0.1 to 6.3±1.2 W·m . Subsequently, the Ni removal efficiencies decreased from 96.9%±3.1% to 73.3%±5.4%. The results clearly demonstrated the feasibility of selective recovery of Cu and Ni from the wastewater using the bioelectrochemical system.

Keywords： bioelectrochemical system     Cu<sup>2+sup>     Ni<sup>2+sup>     selective recovery    

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Advances of 12<sup>thsup> CAPS research symposium: young chemists and chemical engineers fronts

Guoping Hu, Baiqian Dai

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 3,   Pages 461-463 doi: 10.1007/s11705-020-2026-6

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RNA m<sup>6sup>A modification and its function in diseases

Jiyu Tong, Richard A. Flavell, Hua-Bing Li

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 481-489 doi: 10.1007/s11684-018-0654-8

Abstract:

N<sup>6sup>-methyladenosine (m<sup>6sup>A) is the most common post-transcriptional RNAsup>A modification could be installed by m<sup>6sup>A “writers” composed of core catalyticThe function of m<sup>6sup>A is executed by m<sup>6sup>A “readers” that bind to m<supHowever, the mechanism and the regulatory network of m<sup>6sup>A are still largely unknown.Moreover, investigations of the m<sup>6sup>A physiological roles in human diseases are limited.

Keywords： RNA modification     m<sup>6sup>A     immunity     cancer     epigenetics    

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Effect of noble metal nanoparticle size on C–N bond cleavage performance in hydrodenitrogenation: a study of active sites

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 12,   Pages 1986-2000 doi: 10.1007/s11705-023-2337-5

Abstract: Results showed a 13 times higher reaction rate for sp<sup>3sup>-hybridized C–N bond cleavage than sp<sup>2sup>-hybridized C–N bond cleavage, while the reaction rate tended to increase first and then

Keywords： sp<sup>3sup>/sp<sup>2sup>-hybridized C–N bond     noble metal nanoparticle     catalytic active site     turnover    

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Genetic variants in the ADD1 and GNB3 genes and blood pressure response to potassium supplementation

HIXSON PhD, Chung-Shiuan CHEN MS<sup>8sup>, Paul K. WHELTON MD, MSc<sup>9sup>,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 59-66 doi: 10.1007/s11684-010-0015-8

Abstract: Dietary potassium-supplementation has been associated with a decreased risk of hypertension and other cardiovascular outcomes. However, blood pressure (BP) responses to potassium supplementation vary among individuals. This study was designed to examine the association between 12 single nucleotide polymorphisms (SNPs) in the adducin 1 alpha (ADD1) and guanine nucleotide binding protein (G protein) beta polypeptide 3 (GNB3) genes and systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP) responses to potassium-supplementation. We conducted a 7-day high-sodium intervention (307.8 mmol sodium/day) followed by a 7-day high-sodium with potassium-supplementation (60 mmol potassium/day) among 1906 Han Chinese participants from rural north China. BP measurements were obtained at the end of each intervention period using a random-zero sphygmomanometer. We identified significant associations between ADD1 variant rs17833172 and SBP, DBP, and MAP responses to potassium-supplementation (all <0.0001) that remained significant after adjustment for multiple comparisons. In participants that were heterozygous or homozygous for the G allele of this marker, SBP, DBP, and MAP response to potassium-supplementation were −3.52 (−3.82, −3.21), −1.41 (−1.66, −1.15) and −2.12 (−2.37, −1.87), respectively, as compared to the corresponding responses of 1.99 (0.25, 3.73), −0.65 (−0.10, −0.21), and −0.23 (−0.37, 0.83), respectively, for those who were homozygous for A allele. In addition, participants with at least one copy of the G allele of rs12503220 of the ADD1 gene had significantly increased DBP and MAP response to potassium-supplementation ( = 0.0041 and 0.01, respectively), which was also significant after correction for multiple testing. DBP and MAP responses to potassium-supplementation were −1.36 (−1.63, −1.10) and −2.07 (−2.32, −1.82) for those with at least G allele compared to corresponding responses of 0.86 (−0.68, 2.40) and −0.45 (−1.74, 0.84) for those who were homozygous for A allele. In summary, our study identified novel associations between genetic variants of the ADD1 gene and BP response to potassium-supplementation, which could have important clinical and public health implications. Future studies aimed at replicating these novel findings are warranted.

Keywords： blood pressure     genetics     polymorphism     die-tary potassium     potassium sensitivity     adducin 1 alpha (ADD1)     guanine nucleotide binding protein beta polypeptide 3 (GNB3)    

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High frequency of alternative splicing variants of the oncogene in neuroendocrine tumors of the pancreas and breast

Frontiers of Medicine   Pages 907-923 doi: 10.1007/s11684-023-1009-7

Abstract: patients of 33 cancer subtypes, we found that Box 6/Box 7-containing FAK variants (FAK<sup>6/7sup>) were observed in 7 (87.5%) of 8 pancreatic neuroendocrine carcinomas>6/7sup> was positive in 34 (75.6%) of 45 pancreatic NENs, 19 (47.5<sup>6/7sup> in cells.These results suggested that FAK<sup>6/7sup> could be a biomarker of NENs and represent

Keywords： FAK<sup>6/7sup>     SRRM4     neuroendocrine neoplasms     pancreas     breast    

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Effects of La, Ce on nitrogen removal in sequencing batch reactor

Qing XIA , Rui LIANG , Yuning HONG , Lili DING , Hongqiang REN , Yuxiang MAO , Mingyu ZHAO ,

Frontiers of Environmental Science & Engineering 2009, Volume 3, Issue 3,   Pages 369-374 doi: 10.1007/s11783-009-0036-1

Abstract: Batch experiments were conducted to study the short-term biological effects of rare earth ions (La, Ce) and their mixture on the nitrogen removal in a sequencing batch reactor (SBR). The data showed that higher NH―N removal rate, total inorganic nitrogen removal efficiency, and denitrification efficiency were achieved at lower concentrations of rare earth elements (REEs) (<1mg/L). In the first hour of the aeration stage of SBR, the presence of REEs increased the total inorganic nitrogen removal efficiency and NH―N removal efficiency by 15.7% and 10%―15%, respectively. When the concentrations of REEs were higher than 1mg/L, the total inorganic nitrogen removal efficiency decreased, and nitrate was found to accumulate in the effluent. When the concentrations of REEs was up to 50.0mg/L, the total inorganic nitrogen removal efficiency was less than 30% of the control efficiency with a high level of nitrate. Lower concentrations of REEs were found to accelerate the nitrogen conversion and removal in SBR.

Keywords： rare earth     La<sup>3+sup>     Ce<sup>3+sup>     inorganic nitrogen     nitrogen removal     sequencing batch reactor    

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Innate and adaptive T cells in influenza disease

Simone Nüssing, Sneha Sant, Marios Koutsakos, Kanta Subbarao, Thi H.O. Nguyen, Katherine Kedzierska

Frontiers of Medicine 2018, Volume 12, Issue 1,   Pages 34-47 doi: 10.1007/s11684-017-0606-8

Abstract: summarize the current knowledge on influenza-specific innate MAIT and gd T cells as well as adaptive CD8<sup>+sup> and CD4<sup>+sup> T cells, and discuss how these responses can be harnessed by novel vaccine

Keywords： influenza     innate T cells     CD4<sup>+sup> and CD8<sup>+sup> T cells     vaccination    

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NETO2 promotes melanoma progression via activation of the Ca/CaMKII signaling pathway

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 263-274 doi: 10.1007/s11684-022-0935-0

Abstract: proliferation, malignant growth, migration, and invasion by downregulating the levels of calcium ions (Ca<sup>2+sup>) and the expression of key genes involved in the calcium signaling pathway.

Keywords： melanoma     neuropilin and tolloid-like 2     Ca<sup>2+sup>/CaMKII signaling pathway    

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Title Author Date Type Operation

K<sup>+sup> and Na<sup>+sup> fluxes in roots of two Chinese Iris populations

Pinfang LI,Biao ZHANG

Journal Article

Symbiotic performance, shoot biomass and water-use efficiency of three groundnut (

Sofiya K. MUHABA, Felix D. DAKORA

Journal Article

PtHAK5, a candidate for mediating high-affinity K

Haili YANG, Weidan ZHANG, Weiwei CHAI, Wenying WANG, Li GAO, Jing ZHANG, Yongping WANG, Suo-Min WANG

Journal Article

Study on Algorithm A<sup>*sup> Based on Dynamic Representation of Binary Tree for Environment and Robotic

Tang Ping,Yang Yimin

Journal Article

Clinical significance of CD34<sup>+sup>CD117<sup>dimsup>/CD34<sup>+sup>CD117<sup>brisup> myeloblast-associated

Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang

Journal Article

Removal of ammonium and nitrate through Anammox and FeS-driven autotrophic denitrification

Journal Article

Selective recovery of Cu

Haiping LUO,Bangyu QIN,Guangli LIU,Renduo ZHANG,Yabo TANG,Yanping HOU

Journal Article

Advances of 12<sup>thsup> CAPS research symposium: young chemists and chemical engineers fronts

Guoping Hu, Baiqian Dai

Journal Article

RNA m<sup>6sup>A modification and its function in diseases

Jiyu Tong, Richard A. Flavell, Hua-Bing Li

Journal Article

Effect of noble metal nanoparticle size on C–N bond cleavage performance in hydrodenitrogenation: a study of active sites

Journal Article

Genetic variants in the ADD1 and GNB3 genes and blood pressure response to potassium supplementation

HIXSON PhD, Chung-Shiuan CHEN MS<sup>8sup>, Paul K. WHELTON MD, MSc<sup>9sup>,

Journal Article

High frequency of alternative splicing variants of the oncogene in neuroendocrine tumors of the pancreas and breast

Journal Article

Effects of La, Ce on nitrogen removal in sequencing batch reactor

Qing XIA , Rui LIANG , Yuning HONG , Lili DING , Hongqiang REN , Yuxiang MAO , Mingyu ZHAO ,

Journal Article

Innate and adaptive T cells in influenza disease

Simone Nüssing, Sneha Sant, Marios Koutsakos, Kanta Subbarao, Thi H.O. Nguyen, Katherine Kedzierska

Journal Article

NETO2 promotes melanoma progression via activation of the Ca/CaMKII signaling pathway

Journal Article